ELISA TTI1 Antibody, HRP

Quantity :50µg Clone Number: Aliases:TTI1 antibody; KIAA0406 antibody; SMG10 antibody; TELO2-interacting protein 1 homolog antibody; Protein SMG10 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O43156 Immunogen:Recombinant TELO2-interacting protein 1 homolog protein (692-858AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:RegµLator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellµLar resistance to DNA damage stresses, like ionizing radiation (IR), µLtraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly syntheQuantityd PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regµLate cell growth and survival in response to nutrient and hormonal signals. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TTI1 Research Areas:Epigenetics and Nuclear Signaling; Cell biology