BU224 (hydrochloride) (Standard) [205437-64-5]

BU224 (hydrochloride) (Standard) [205437-64-5] : Size : 1L - Certification : Research Use Only - BU224 (hydrochloride) (Standard) is the analytical standard of BU224 (hydrochloride). This product is intended for research and analytical applications. BU224 hydrochloride is a selective and high affinity imidazoline I2 receptor ligand, with a Ki of 2.1 nM. BU224 hydrochloride is sometimes used as an I2 receptor antagonist. BU224 hydrochloride exerts neuroprotective effects, with anti-inflammatory and anti-apoptotic properties. BU224 hydrochloride improves memory in 5XFAD mice, enlarging dendritic spines and reducing Abeta-induced changes in NMDARs. BU224 hydrochloride can be used for Alzheimers disease research[1][2][3]. -